Research Article

Y-Box Binding Protein 1 Regulates Angiogenesis in Bladder Cancer via miR-29b-3p-VEGFA Pathway

Figure 4

VEGFA was confirmed as one of the target genes of YB-1 by experiments and bioinformatics analysis. (a) miR-29b-3p may bind the sequence (UGGUGCU) in 3′ UTR of VEGFA to function according to TargetScanHuman 7.1. (b–d) miR-29b-3p was inhibited by miRNAs inhibitor in YB-1 KD-EJ cells. Then, the relative expression level of VEGFA was measured by RT-qPCR and Western Blot. YB-1 KD, YB-1 knockdown; 3′ UTR, 3′‐untranslated region; NC, negative control; miR, microRNA; ih, inhibitor; and .
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