miR-455 Inhibits the Viability and Invasion by Targeting RAB18 in Hepatocellular Carcinoma

Figure 2

miR-455 inhibits cell viability of HCC in vitro and in vivo. (a) miR-455 mimic and miR-455 inhibitor were used to upregulate or downregulate the expression of miR-455 vs mimic NC or inhibitor NC, ^∗P < 0.05, ^∗∗P < 0.01. (b) The proliferative ability was decreased after transfection with miR-455 mimic vs mimic NC, ^∗P < 0.05. (c) miR-455 inhibitor increased proliferative ability in comparison with normal control vs inhibitor NC, ^∗P < 0.05. (d) miR-455 suppressed the growth of HCC in vivo vs inhibitor NC, ^∗P < 0.05; ^∗∗P < 0.01. (e) Tumors of miR-455 overexpressed group had a smaller volume than that of control group vs inhibitor NC, ^∗P < 0.05.

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