miR-455 Inhibits the Viability and Invasion by Targeting RAB18 in Hepatocellular Carcinoma

Figure 4

miR-455 targets RAB18 and regulates its expression. (a) TargetScan predicted that RAB18 was a potential target of miR-455. (b) miR-455 mimic reduced the luciferase ability of wild type mRNA 3′-UTR, whereas it did not alter the mutant 3′-UTR vs WT-NC, ^∗P < 0.05 and vs MUT-NC, ^#P < 0.05. (c) The expression of RAB18 was decreased by miR-455 mimic, while it was promoted by miR-455 inhibitor in Huh7 cells vs mimic NC, ^∗P < 0.05 and vs inhibitor NC, ^∗P < 0.05.

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