Research Article

Efficacy and Safety of Regorafenib Combined with Toripalimab in the Third-Line and beyond Treatment of Advanced Colorectal Cancer

Table 1

Clinical information of 33 advanced colorectal cancer patients (n = 33).

CharacteristicsStatistics

Sex (male/female)15/18
Age (years)53.64 ± 10.34
ECOG (0/1)10/23
Primary tumor location (left/right)23/10
Liver metastases (yes/no)20/13
Lung metastases (yes/no)28/5
Lymph node metastasis (yes/no)22/11
Excision of primary lesion (yes/no)29/4
Number of previous chemotherapy lines
 (2/3 lines or above)16/17
 Regorafenib (80 mg/120 mg)23/10
 KRAS genetic testing (yes/no)21/12
 KRAS (wild/mutation)13/8

Previous chemotherapeutic drug
 Fluorouracil (yes/no)33/0
 Oxaliplatin (yes/no)33/0
 Irinotecan (yes/no)33/0
 Raltitrexed (yes/no)12/21

Previously targeted drugs
 Bevacizumab (yes/no)28/5
 Cetuximab (yes/no)11/22

ECOG, Eastern Cooperative Oncology Group performance status.