Mechanism of PDZK1 in Hepatocellular Carcinoma Complicated with Hyperuricemia

Figure 5

Allopurinol is an effective drug to improve the prognosis of HCC; (a) the tumor volume of PDZK1 overexpression group are increased, and treat with Allopurinol, the tumor volume is decreased; (b) Ki67 result showed that after treatment with Allopurinol, the proliferation of tumor was more reduced compare with PDZK1 overexpression group; (c) immunofluores result showed that,the p-STAT3 and C-myc expression was increased in PDZK1 overexpression group, and p-STAT3 and C-myc was decreased after treatment with allopurino.

(a)

(b)

(c)