TRIP13/FLNA Complex Promotes Tumor Progression and Is Associated with Unfavorable Outcomes in Melanoma

Table 1

Correlations between TRIP13 with clinicopathologic features in 123 melanoma patients.

Variable	Number of patients		value
	TRIP13^low	TRIP13^high
Age (year)
<60	25	24	0.397
≥60	32	42
Gender
Male	33	30	0.169
Female	24	36
Ulceration
Present	45	58	0.181
Absent	12	8
Breslow depth (mm)
≤2	33	29	0.123
>2	24	37
Clark level
I-III	33	33	0.381
IV-V	24	33
Lymph node metastasis
No	50	42	0.002
Yes	7	24
Distant metastasis
No	46	41	0.024
Yes	11	25
Clinical stage
I-II	33	42	0.515
III-IV	24	24

Note: a chi-square test was used for comparing groups between low and high TRIP13 expression.