TRIP13/FLNA Complex Promotes Tumor Progression and Is Associated with Unfavorable Outcomes in Melanoma

Table 2

Univariate and multivariate analyses of factors associated with overall survival.

Variable	Overall survival
	Multivariate analysis
	Univariate	HR	95% CI
Age (year) (≥60 vs. <60)	0.166			NA
Gender (men vs. women)	0.195			NA
Ulceration (present vs. absent)	0.149			NA
Breslow depth (mm) (≤2 vs. >2)	0.543			NA
Clark level (I-III vs. IV-V)	0.104			NA
Lymph node metastasis (yes vs. no)	0.143			NA
Distant metastasis (yes vs. no)	0.003	1.44	0.837-2.478	0.188
Clinical stage (yes vs. no)	0.03	1.59	0.947-2.671	0.079
TRIP13 staining (low vs. high)	0.003	1.933	1.171-3.188	0.01

Note: NA: not adopt; value was calculated using Cox proportional hazards regression.