Ai-Tong-An-Gao-Ji and Fisetin Inhibit Tumor Cell Growth in Rat CIBP Models by Inhibiting the AKT/HIF-1α Signaling Pathway

Figure 5

Fisetin affects the Akt/HIF-1α signaling pathway in tumor cells. (a) Coimmunoprecipitation assay showed fisetin-AKT interactions in Walker 256 cells. (b) Protein expressions of p-Akt, HIF-1α, and VEGF. (c, d) HIF-1α and VEGF were detected by immunofluorescence assay. Red represented HIF-1α and VEGF. Blue represented DAPI.

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