Up-Regulation of SH3TC2 Induced by YTHDF1 Predicts Poor Outcome and Facilitates Cell-Cycle Progress in Colorectal Cancer

Figure 1

Pan-cancer analysis based on the GEPIA database reveals that SH3TC2 is dysregulated in 9 human cancer types. (a) SH3TC2 was upregulated in 404 BLCA samples compared with 28 normal samples, . T represents tumor, and N represents normal. (b) SH3TC2 was increased in 36 CHOL samples compared with 9 normal samples, . (c) SH3TC2 was elevated in 275 COAD samples compared with 349 normal samples, . (d) SH3TC2 was overexpressed in 173 LAML specimens compared with 70 normal specimens, . (e) SH3TC2 was highly expressed in 179 PAAD specimens compared with 171 normal specimens, . (f) SH3TC2 was upregulated in 92 READ specimens compared with 318 normal specimens, . (g) SH3TC2 was elevated in 461 SKCM tissues compared with 558 normal tissues, . (h) SH3TC2 was decreased in 1085 BRCA tissues compared with 291 normal tissues, . (i) SH3TC2 was downregulated in 137 TGCT tissues compared with 165 normal tissues, .

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