Research Article
Prognosis and Prognostic Factors of Serous Borderline Tumor-Micropapillary Variant: Retrospective Study of 200 Patients with Long-Term Follow-Up
Table 3
Prognostic factors for invasive recurrence in women with SBOT-Ms (
).
| | Variables | Invasive disease-free survival (DFS) | | Univariate analysis | Multivariate analysis | | N. lethal recur./total (%) | 5-year invasive DFS (%) | value | Hazard ratio (95% CI) | value |
| | Age (years) | ≤ 35 | 18/125 (14.4) | 87 | .165 | | | | >35 | 5/75 (6.7) | 93 | | | | | Nulliparous | No | 4/92 (4.3) | 95 | .009 | 1 | .022 | | Yes | 19/108 (17.6) | 86 | | 3.5 (1.2-10.4) | | | Surgical approach | Laparotomy | 17/134 (12.7) | 88 | .574 | | | | Laparoscopy | 6/66 (9.1) | 92 | | | | | Staging surgery | Yes | 15/127 (11.8) | 90 | .774 | | | | No | 8/73 (11.0) | 89 | | | | | Lymphadenectomy | Yes | 7/60 (11.7) | 93 | >.999 | | | | No | 16/140 (11.4) | 89 | | | | | Surgical extent | Radical | 7/78 (9.0) | 90 | 0.452 | | | | Conservative | 16/122 (13.1) | 88 | | | | | Ovarian involvement | Unilateral | 2/63 (3.2) | 96 | .015 | 1 | .112 | | Bilateral | 21/137 (15.3) | 87 | | — | | | FIGO stage† | I | 7/106 (6.6) | 95 | .014 | 1 | .029 | | II-IV | 16/94 (17.0) | 83 | | 1.6 (1.1-2.6) | | | Stromal microinvasion | No | 17/164 (10.4) | 92 | .221 | | | | Yes | 6/36 (16.7) | 77 | | | | | Type of implants () | Noninvasive | 11/68 (16.2) | 83 | .657 | | | | Invasive | 5/26 (19.2) | 77 | | | | | Chemotherapy | No | 13/146 (8.9) | 93 | .101 | | | | Yes | 10/54 (18.5) | 80 | | | |
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†FIGO, International Federation of Gynecology and Obstetrics.
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