A Nomogram Combining MRI Multisequence Radiomics and Clinical Factors for Predicting Recurrence of High-Grade Serous Ovarian Carcinoma

<div>(a–d) A 54-year-old female was diagnosed with bilateral ovarian high-grade serous carcinoma (HGSOC, FIGO IIIC) by postoperative pathology on April 18, 2019. Postoperative chemotherapy was performed six times with TC regimen [<svg height="14.9947pt" id="M6" style="vertical-align:-3.4033pt" version="1.1" viewbox="-0.0498162 -11.5914 244.988 14.9947" width="244.988pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M517 51L485 54C448 58 441 63 441 115V712C404 700 337 684 285 678V653C357 648 362 645 362 580V437C339 446 309 449 295 449C159 449 38 340 38 201C38 61 143 -12 223 -12C234 -12 261 -6 301 17L362 53V-12C420 9 495 22 517 26V51ZM362 85C338 67 301 51 266 51C201 51 128 109 128 228C128 373 212 411 259 411C296 411 338 395 362 360V85Z"></path></g><g transform="matrix(.013,0,0,-0.013,6.864,0)"><path d="M257 449C165 449 37 374 37 209C37 98 119 -12 256 -12C355 -12 473 65 473 226C473 349 381 449 257 449ZM244 416C333 416 380 320 380 204C380 67 329 21 267 21C184 21 130 115 130 241C130 354 184 416 244 416Z"></path></g><g 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270Z"></path></g></svg>]. (e) Reexamination of chest+abdominal CT and pelvic MRI on January 20, 2020. No clear recurrent diseases were found. (f, g) On April 25, 2021, the CA125 was elevated, and CT examination revealed thickening of the abdominal peritoneum with multiple nodules (red and blue arrow) and pelvic effusion, so recurrence was considered. DFS was 24 months.</div>

Journal of Oncology

fig1

Figure 1

Figure 1: A Nomogram Combining MRI Multisequence Radiomics and Clinical Factors for Predicting Recurrence of High-Grade Serous Ovarian Carcinoma 