Association of ERCC1 rs11615 Polymorphism with the Risk of Cervical Cancer Especially in Chinese Populations: A Meta-Analysis

Table 4

The main results of the meta-analysis.

Groups (quantity of studies)	Cases/controls	Genetic model	Effects model	Test of association			Test of heterogeneity		Begg’s		Egger’s
				OR	95% CI		(%)
Overall (6)	753/851	T vs C	Random	1.199	0.819-1.754	0.351	80.2	0.000	1.88	0.060	1.77	0.152
		TT vs CC	Random	1.720	0.757-3.908	0.195	72.3	0.003	1.50	0.133	2.98	0.041
		TC vs CC	Fixed	0.992	0.800-1.229	0.938	44.7	0.108	0.75	0.452	1.32	0.256
		TT/CT vs CC	Random	1.140	0.774-1.680	0.506	70.2	0.005	1.13	0.260	1.83	0.142
		TT vs CT/CC	Random	1.633	0.789-3.379	0.187	66.1	0.012	1.50	0.133	3.00	0.040
China (4)	314/447	T vs C	Fixed	1.557	1.234-1.966	0.000	0.0	0.806	1.02	0.308	1.45	0.283
		TT vs CC	Fixed	3.175	1.754-5.748	0.000	0.0	0.840	1.02	0.308	1.17	0.361
		TC vs CC	Fixed	1.308	0.958-1.786	0.091	0.0	0.893	0.34	0.734	0.10	0.927
		TT/CT vs CC	Fixed	1.512	1.126-2.031	0.006	0.0	0.896	0.34	0.734	0.67	0.571
		TT vs CT/CC	Fixed	2.836	1.592-5.051	0.000	0.0	0.768	1.70	0.089	1.15	0.370
Conform to HWE ()
Overall (4)	448/530	T vs C	Random	1.395	1.015-1.918	0.040	51.9	0.101	1.02	0.308	2.60	0.121
		TT vs CC	Fixed	1.983	1.176-3.344	0.010	30.8	0.227	1.02	0.308	2.04	0.178
		TC vs CC	Fixed	1.175	0.895-1.543	0.245	0.0	0.561	-0.34	1.000	1.45	0.284
		TT/CT vs CC	Fixed	1.280	0.989-1.657	0.061	23.4	0.271	0.34	0.734	2.24	0.155
		TT vs CT/CC	Fixed	1.855	1.113-3.093	0.018	18,5	0.298	1.02	0.308	2.07	0.174
China (3)	219/326	T vs C	Fixed	1.647	1.244-2.181	0.000	0.0	0.779	0.00	1.000	0.96	0.514
		TT vs CC	Fixed	3.004	1.543-6.008	0.001	0.0	0.682	1.04	0.296	0.83	0.558
		TC vs CC	Fixed	1.414	0.972-2.058	0.070	0.0	0.960	1.04	0.296	-1.17	0.450
		TT/CT vs CC	Fixed	1.630	1.146-2.319	0.007	0.0	0.987	0.00	1.000	0.80	0.570
		TT vs CT/CC	Fixed	2.661	1.374-5.154	0.004	0.0	0.616	1.04	0.296	0.84	0.555