Research Article

Pretreatment Neutrophil-to-Lymphocyte Ratio and Lactate Dehydrogenase Predict the Prognosis of Metastatic Cervical Cancer Treated with Combination Immunotherapy

Table 1

General characteristics of patients with metastatic cervical cancer treated with combination immunotherapy.

Variables (%)

Median age, years (range)51 (29–77)
Histology
 Squamous cell carcinoma54 (77.14)
 Adenocarcinoma or others16 (22.86)
Disease status
 Local recurrence27 (38.57)
 Distant metastasis43 (61.43)
Prior radiotherapy
 Yes56 (80.00)
 No14 (20.00)
Line of immunotherapy
 First-line or second-line46 (65.71)
 Third-line or more24 (34.29)
NLR5.17 (3.19–9.16)
PLR270.50 (174.19–363.49)
MLR0.51 (0.31–0.78)
SCC-Ag (ng/mL)2.85 (0.90–14.10)
AGR1.50 (1.30–1.63)
LDH (U/L)166.50 (146.75–195.75)
ALP (U/L)87.50 (70.00–106.00)

Abbreviations: AGR, albumin-to-globulin ratio; ALP, alkaline phosphatase; LDH, lactate dehydrogenase; MLR, monocyte-to-lymphocyte ratio; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; SCC-Ag, squamous cell carcinoma-associated antigen.