Development and Validation of a Combined Ferroptosis and Immune Prognostic Model for Melanoma

Figure 8

mRNA and protein level validation of PDGFRB and FOXM1 and the functional analysis in melanoma against normal samples. (a, b) The mRNA and protein expression of two genes based on melanocytes (PIG1) and melanoma cells (A375, A875, and MeWo). (c) IHC examination of PDGFRB and FOXM1 in healthy and malignant tissue. (d) Transfection efficiency of A375 cells. (e) CCK8 assay (A375). (f) Colony formation assays (A375). Data represent mean ±SD (standard deviation); ^∗P < 0.05, ^∗∗P < 0.01 and ^∗∗P < 0.001 (versus control group).

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