SIRT6 Promotes the Progression of Prostate Cancer via Regulating the Wnt/β-Catenin Signaling Pathway

Figure 2

Knockdown of SIRT6 suppressed the proliferation of PC-3 or DU145 cells. (a) qPCR assays detected the expression levels of SIRT6 in PCa cells after transfected with si-SIRT6 or si-NC. (b, c) CCK-8 assays evaluated the cellular growth after treatment with si-SIRT6 or si-NC at 48 h, 72 h, and 96 h. (d and e) Colony formation assays assessed the effects of SIRT6 knockdown on the clonogenic capacity of PCa cells. .

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