Adjuvant Chemotherapy in Node-Negative Advanced Gastric Cancer Patients

Table 2

Univariate and multivariate survival analysis of clinicopathologic variables in 363 cases of gastric carcinoma patients.

Variables	Univariate analysis			Multivariate analysis
	HR	95% CI	value	HR	95% CI	value
Gender (male vs. female)	0.846	0.555–1.292	0.439
Age (year) (≥60 vs. <60)	1.313	0.896–1.922	0.162
Location (distal/proximal/total)	1.047	0.737–1.487	0.799
Size (cm) (<2.5/2.5–5/>5)	2.980	2.115–4.199	<0.001	3.105	2.038–4.730	<0.001
Differentiation (G3/G2 vs. G1)	1.633	1.286–2.074	<0.001	1.553	1.221–1.974	<0.001
Lymphovascular invasion (no vs. yes)	16.380	8.441–31.787	<0.001	8.540	4.285–17.021	<0.001
Chemotherapy (yes vs. no)	1.206	0.827–1.757	0.333
T stage (T4b/T4a/T3/T2)	1.717	1.335–2.207	<0.001	1.332	1.024–1.734	0.033
Retrieved lymph nodes (<15 vs. ≥15)	0.347	0.213–0.565	<0.001	0.414	0.253–0.678	0.001

HR, hazard ratio; CI, confidence interval; AFP, alpha-fetoprotein. Statistically significant ().