Overexpression of PTPRZ1 Regulates p120/-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis

Figure 3

Overexpression of PTPRZ1 promoted cell proliferation, migration, and invasion. (a) CCK-8 detected the proliferation rate of cells in each group at 12 h, 24 h, 48 h, 72 h, 96 h h, and 120 h (n = 3). (b, c) Wound healing detected cell migration ability (n = 3). (d–f) Transwell assay detected the migration and invasion ability of cells in each group (n = 3). (g, h) Flow cytometry was applied to detect cell cycle in each group (n = 3). (i, j) Annexin V-FITC/PI flow cytometry detected the apoptosis rate of cells in each group (n = 3). vs. the OSF group (hOMF cells); vs. the oe-NC group (hOMF cells); scale bar = 100 µm; and the magnification is 100 times.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)

(j)