Overexpression of PTPRZ1 Regulates p120/-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis

Figure 6

Silencing PTPRZ1 inhibited the development of OSCC. (a) Tumor formation in nude mice was observed by photographing (n = 3). (b) The tumor volume of nude mice in each group was measured at each time point of t 4 d, 7 d, 11 d, 14 d, 17 d, 21 d, and 24 d (n = 3). (c) The nude mice were sacrificed on 24 days, and the tumor weight of each group of nude mice was measured (n = 3). (d) PTPRZ1 positive rate in tumor tissue was detected by IHC (n = 3). vs. the OSCC group (CAL27 cells); scale bar = 25 µm; and the magnification is 400 times.

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