Long Noncoding RNA SNHG16 Regulates the Growth of Human Lung Cancer Cells by Modulating the Expression of Aldehyde Dehydrogenase 2 (ALDH2)

Figure 7

SNHG16 knockdown suppresses in vivo mice tumor xenograft growth. (a) Analysis of tumor size from the mice administered with si-SNHG16 or si-NC; (b) expression of SNHG16 in mice tumors administered with si-SNHG16 or si-NC; (c) H&E staining of si-NC and si-SNHG16 tumors; (d) IHC showing expression of ALDH2 protein in si-SNHG16 or si-NC tumors; (e) analysis of tumor volume at indicated study stages from the mice administered with si-SNHG16 or si-NC; (f) average weight of si-SNHG16 or si-NC tumors; (g) western blotting showing expression of Bax, Bcl-2, and cleaved caspase-3 in si-NC or si-SNHG16 tumors ().

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