Screening of the Key Genes for the Progression of Liver Cirrhosis to Hepatocellular Carcinoma Based on Bioinformatics

Figure 1

Differentially expressed genes (DEGs) between HCC and cirrhotic liver tissues identified in GSE25097 and GSE17549 datasets. (a) A total of 627 genes were found to be elevated and 1716 genes depressed in HCC tissues as compared to cirrhotic liver tissues in the GSE25097 dataset. (b) The expression profiles of each of the top 20 DEGs identified from the GSE25097 dataset. (c) A total of 149 genes were found to be elevated and 285 genes depressed in HCC tissues as compared to cirrhotic liver tissues in the GSE17548 dataset. (d) The expression profiles of each of the top 20 DEGs in the GSE17548 dataset.

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