circNBPF10/miR-224 Axis Regulates PBX3 to Promote the Malignant Progression of Lung Cancer

Figure 5

miR-224 inhibits PBX3 expression. (a) Information maps of miR-224 and PBX3 binding sites. (b) Dual luciferase reporter gene assay verified the combination of miR-224 and PBX3. (c) miRNA pull-down assay. (d) Verification of miR-224 expression. (e) miR-224 overexpression mimics inhibited the expression of PBX3. The content of PBX3 increased with the addition of the miR-224 inhibitor. (f) Correlation analysis of PBX3 and miR-224 coexpression. (g) Correlation analysis of circNBPF10 and PBX3 coexpression. (h) PBX3 expression in tumors detected by qRT-PCR.  < 0.01.

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