Hax-1 Regulates Radiation-Induced Mitochondrial-Dependent Apoptosis of Uveal Melanoma Cells through PI3K/AKT/eNOS Pathway

Figure 4

HAX-1 induces apoptosis in the mitochondrial-dependent pathway. (a) Flow cytometry to detect flow cytometry cycle distribution. (b) WB assay to identify Bax and Bcl-2 protein expressing levels in UM lineage cells MUM-2B and C91. (c) Western blot analysis to detect the expression levels of caspase-3/9 and cytosolic Cyt c protein in the uveal melanoma cell lines MUM-2B and C91. (d) Immunofluorescence detection of MMP expressing in UM lineage cells MUM-2B and C91.

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