Survival Outcome of Partial Cystectomy versus Transurethral Bladder Tumor Resection in T1 High-Grade Bladder Cancer Patients: A Propensity Score Matching Study
Table 1
Clinicopathological features between TURBT and PC before and after propensity score matching.
Variables
No PSM
PSM
TURBT (n = 24635)
PC (n = 190)
value
TURBT (n = 190)
PC (n = 190)
value
Age (year)
Mean ± SD
72.9 ± 10.371
71.5 ± 9.830
0.014∗
72.7 ± 11.448
71.5 ± 9.830
0.260
Median (25th–75th percentile)
72 (67.5–82)
72 (67.5–77.5)
0.016∗
77.5 (62–82)
72 (67.5–77.5)
0.068
Sex
0.041∗
0.769
Female
5115 (20.8%)
28 (14.7%)
26 (13.7%)
28 (14.7%)
Male
19520 (79.2%)
162 (85.3%)
164 (86.3%)
162 (85.3%)
Race
0.572
0.072
White
21859 (88.7%)
171 (90.0%)
162 (85.3%)
171 (90.0%)
Black
1448 (5.9%)
12 (6.3%)
10 (5.3%)
12 (6.3%)
Other style
1328 (5.4%)
7 (3.7%)
18 (9.5%)
7 (3.7%)
Marital status
0.055
0.859
Married
15420 (62.6%)
132 (69.5%)
135 (71.1%)
132 (69.5%)
SDW
6285 (25.5%)
34 (17.9%)
30 (15.8%)
34 (17.9%)
Single
2930 (11.9%)
24 (12.6%)
25 (13.2%)
24 (12.6%)
Grade
0.544
0.090
Grade I or Grade II
517 (2.1%)
6 (3.2%)
2 (1.1%)
6( 3.2%)
Grade III
4926 (20.0%)
40 (21.1%)
55 (28.9%)
40 (21.1%)
Grade IV
19192 (77.9%)
144 (75.8%)
133 (70.0%)
144 (75.8%)
Histology
0.119
0.047∗
TCC
7527 (30.6%)
68 (35.8%)
87 (45.8%)
68 (35.8%)
PTCC
17108 (69.4%)
122 (64.2%)
103 (54.2%)
122 (64.2%)
Radiotherapy
0.535
0.2
No/unknown
24081 (97.8%)
187 (98.4%)
183 (96.3%)
187 (98.4%)
Yes
554 (2.2%)
3 (1.6%)
7 (3.7%)
3 (1.6%)
Chemotherapy
0.127
0.618
No/unknown
18389 (74.6%)
151 (79.5%)
147 (77.4%)
151 (79.5%)
Yes
6246 (25.4%)
39 (20.5%)
43 (22.6%)
39 (20.5%)
Tumor size
0.267
<0.001∗
≤3 cm
10919 (44.3%)
78 (41.1%)
129 (67.9%)
78 (41.1%)
3–6 cm
9833 (39.9%)
74 (38.9%)
54 (28.4%)
74 (38.9%)
>6 cm
3883 (15.8%)
38 (20.0%)
7 (3.7%)
38 (20.0%)
Tumor site
<0.001∗
<0.001∗
Trigone
1266 (5.1%)
1 (0.5%)
19 (10.0%)
1 (0.5%)
Dome
1235 (5.0%)
29 (15.3%)
11 (5.8%)
29 (15.3%)
Lateral
4941 (20.1%)
30 (15.8%)
35 (18.4%)
30 (15.8%)
Anterior
704 (2.9%)
10 (5.3%)
8 (4.2%)
10 (5.3%)
Posterior
2453 (10.0%)
22 (11.6%)
23 (12.1%)
22 (11.6%)
Bladder neck
784 (3.2%)
2 (1.1%)
7 (3.7%)
2 (1.1%)
Ureteric orifice
584 (2.4%)
4 (2.1%)
4 (2.1%)
4 (2.1%)
Other sites
12668 (51.4%)
92 (48.4%)
83 (43.7%)
92 (48.4%)
Number of tumors
0.880
<0.001∗
Single
14655 (59.5%)
112 (58.9%)
74 (38.9%)
112 (58.9%)
Multiple
9980 (40.5%)
78 (41.1%)
116 (61.1%)
78 (41.1%)
Survival time (month)
Mean
47.498
55.121
<0.001∗
51.763
55.121
0.015∗
Median (25th–75th percentile)
55 (37–77)
55.5 (37–77)
<0.001∗
48 (23–81.25)
55.5 (37–77)
0.236
PC: partial cystectomy; TURBT: transurethral bladder tumor resection; other race: American/Indian/Alaska/Native/Asian/Pacific Islande; SDW: separated, divorced or widowed; other sites: overlapping lesion of bladder, bladder, NOS; TCC: transitional cell carcinoma, PTCC: papillary transitional cell carcinoma. PSM, propensity score matching. ∗Statistically significant.
