Establishment and Identification of Patient-Derived Xenograft Model for Oral Squamous Cell Carcinoma
Table 1
Clinicopathological features of primary tumor patients with the PDX model of OSCC.
Age
Gender
Location
Pathology
TNM stage
42
M
Left lingual edge
Highly differentiated squamous cell carcinoma.
T2N0M0
54
M
Right lingual edge
Highly differentiated squamous cell carcinoma.
T2N0M0
61
F
Right cheek
Keratinizing squamous cell carcinoma with invasion of transverse muscle tissue.
T3N0M0
54
M
Lower left gum
Moderately differentiated squamous cell carcinoma, invading bone tissue.
T4aN0M0
74
M
Right lingual edge
Keratinizing squamous cell carcinoma with invasion of submucosal transverse muscle tissue and salivary gland tissue.
T4aN0M0
44
M
Right lingual edge
Squamous cell carcinoma with invasion of the transverse muscle and metastasis to one lymph node.
T3N1M0
48
M
Right lingual edge
Squamous cell carcinoma, invading the transverse muscle and salivary gland tissue and a lymph node metastasis.
T4aN1M0
74
F
Left lingual edge
Squamous cell carcinoma with two lymph node cancer metastases visible in the left neck.
T3N2bM0
88
M
Lower left gum
Highly differentiated squamous cell carcinoma invading transverse muscle and bone tissue, two lymph node carcinoma metastases visible in the left neck.
T4aN2aM0
44
F
Right lingual edge
Keratinizing squamous cell carcinoma with invasion of transverse muscle tissue and two lymph node cancer metastases in the right neck.
T4aN2bM0
68
M
Left lingual edge
Squamous cell carcinoma with invasion of transverse muscle tissue. One lymph node metastasis was seen in the left neck. Two lymph node carcinoma metastases were seen in the right neck.
T4aN2cM0
42
M
Left lingual edge
Squamous cell carcinoma involves transverse muscle tissue invading the nerve. Four lymph node carcinoma metastases were seen in the left neck and three lymph node carcinoma metastases were seen in the right submandibular.
