Integrated Machine Learning and Single-Sample Gene Set Enrichment Analysis Identifies a TGF-Beta Signaling Pathway Derived Score in Headneck Squamous Cell Carcinoma

<div>Construction of TGF-β signal score in eight datasets. (a) The scatter diagram indicated the distribution of TGF-β signal score across eight datasets. (b) The scatter diagram exhibited the TGF-β signal score in HNSC and normal samples. (c) Relationship between TGF-β signal score, HPV infection status, M stage and clinical stage in TCGA_HNSC and GEO database. (d) The top 8 results of GO analysis (BP, CC, and MF) in TGF-β signal pathway_H (red) and TGF-β signal pathway_L (blue). (e) The results of KEGG analysis in TGF-β signal pathway_H (red) and TGF-β signal pathway_L (blue).</div>

Journal of Oncology

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Figure 1: Integrated Machine Learning and Single-Sample Gene Set Enrichment Analysis Identifies a TGF-Beta Signaling Pathway Derived Score in Headneck Squamous Cell Carcinoma 

Figure 1 | Integrated Machine Learning and Single-Sample Gene Set Enrichment Analysis Identifies a TGF-Beta Signaling Pathway Derived Score in Headneck Squamous Cell Carcinoma 