Research Article
Deficiency of kin17 Facilitates Apoptosis of Cervical Cancer Cells by Modulating Caspase 3, PARP, and Bcl-2 Family Proteins
Figure 3
Effect of kin17 knockdown on the expression profile of apoptosis-associated proteins in cervical cancer cells. activities of caspase 3 in kin17KD and kin17Mock cells was normalized to the kin17NC cells (a), the average value of which was set as 100%, , nā=ā3. total-length PARP, cleaved PARP, Bim, Bcl-xL, bad, phosphorylated bad in HeLa and SiHa cells were detected via western blotting (b). NC, negative control; KD, knockdown; PARP, poly ADP-ribose polymerase; Bim, Bcl-2 interacting mediator of cell death; Bcl-xL, B-cell lymphoma-xL; Bad, Bcl2 associated death promoter.
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