Histone Deacetylase Inhibitor I3 Induces the Differentiation of Acute Myeloid Leukemia Cells with <i>t</i> (8; 21) or MLL Gene Translocation and Leukemic Stem-Like Cells

<div>I3 inhibited the proliferation of Kasumi-1, KG-1, MOLM-13, and THP-1 cells. (a) The chemical structure of I3 and SAHA. (b) CCK-8 assay on cells treated with I3 or SAHA (0–10 <i>μ</i>M) for 72 h. Data represented as mean ± SD.</div>

Journal of Oncology

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Figure 1

Figure 1: Histone Deacetylase Inhibitor I3 Induces the Differentiation of Acute Myeloid Leukemia Cells with <i>t</i> (8; 21) or MLL Gene Translocation and Leukemic Stem-Like Cells 

Figure 1 | Histone Deacetylase Inhibitor I3 Induces the Differentiation of Acute Myeloid Leukemia Cells with t (8; 21) or MLL Gene Translocation and Leukemic Stem-Like Cells 