Histone Deacetylase Inhibitor I3 Induces the Differentiation of Acute Myeloid Leukemia Cells with t (8; 21) or MLL Gene Translocation and Leukemic Stem-Like Cells

Figure 3

I3 induces the differentiation of Kasumi-1, KG-1, MOLM-13, and THP-1 cells. (a) The morphology of Wright-Giemsa-stained cells captured by oil immersion lens (×1,000). (b) The expression of antigens of cells measured by flow cytometry. (c) Graph bars present the mean fluorescence intensity (MFI) of antigens. Kasumi-1, KG-1, MOLM-13, and THP-1 cells were incubated with 0.25, 1.2, 0.9, or 1.2 μM of I3 for 72 h (, ).

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