Histone Deacetylase Inhibitor I3 Induces the Differentiation of Acute Myeloid Leukemia Cells with <i>t</i> (8; 21) or MLL Gene Translocation and Leukemic Stem-Like Cells

<div>I3 suppresses colony formation in Kasumi-1, KG-1, MOLM-13, and THP-1 cells. (a) Cells were treated with I3 at concentrations of 0.5–2 <i>μ</i>M for 14 days, and the cell morphology was observed under light microscopy. (b) The effect of different concentrations of I3 on colony formation.</div>

Journal of Oncology

fig5

Figure 5

Figure 5: Histone Deacetylase Inhibitor I3 Induces the Differentiation of Acute Myeloid Leukemia Cells with <i>t</i> (8; 21) or MLL Gene Translocation and Leukemic Stem-Like Cells 

Figure 5 | Histone Deacetylase Inhibitor I3 Induces the Differentiation of Acute Myeloid Leukemia Cells with t (8; 21) or MLL Gene Translocation and Leukemic Stem-Like Cells 