Maslinic Acid Inhibits the Growth of Malignant Gliomas by Inducing Apoptosis via MAPK Signaling

Figure 6

Maslinic acid induces U251 cell apoptosis. (a) Western blot analysis showed the changes in the MAPK signal pathway and apoptosis-related proteins in U87 and U251 cells. Maslinic acid inhibits the MAPK signal pathway which promotes the apoptosis of tumor cells and exerts its antitumor effect. (b) Downregulated MAPK signaling members (log2 FRKM). (c) Upregulated MAPK signaling members (log2 FRKM). (d) Apoptosis signaling members’ expression change (log2 FRKM).

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