Uncovering the Immune Cell Infiltration Landscape in Low-Grade Glioma for Aiding Immunotherapy

Figure 1

Characterization of ICI subtypes with distinct survival outcomes for LGG in TCGA-LGG dataset. ((a)–(c)) Unsupervised clustering analysis for classifying three ICI subtypes by the “ConsensusClusterPlus” package. (a) Consensus cumulative distribution function graph. (b) Delta area plot. (c) Heatmap for consensus matrix when k = 3. (d) PCA plots for the classification patterns of the ICI subtypes. (e) Heatmap of tumor-infiltrating immune cells in different clinical phenotypes and ICI subtypes. (f) Kaplan-Meier curves for OS of LGG patients in the three ICI subtypes.

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