SNHG3 Affects Gastric Cancer Development by Regulating SEPT9 Methylation

<div>miR-448 regulates SEPT9 methylation, invasion, migration, and proliferation through DNMT1. (a) qRT–PCR detection of the expression of SNHG3; (b) MSP detection of the methylation level of SEPT9; (c) WB detection of the expression of DNMT1 and SEPT9; (d) Transwell assay detection of the invasion ability of GC cells, <span class="nowrap"><svg height="12.7373pt" id="M30" style="vertical-align:-3.429399pt" version="1.1" viewbox="-0.0498162 -9.3079 104.595 12.7373" width="104.595pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M319 325C317 349 306 409 297 431C277 440 250 449 209 449C117 449 57 389 57 319C57 243 122 209 182 182C232 159 261 135 261 91C261 48 227 21 190 21C130 21 85 79 68 145L41 140C41 104 51 36 58 22C75 7 121 -12 172 -12C252 -12 337 35 337 126C337 195 286 231 210 262C166 281 126 304 126 348C126 388 152 417 191 417C240 417 274 378 294 318L319 325Z"></path></g><g transform="matrix(.013,0,0,-0.013,4.875,0)"><path d="M390 111C344 68 312 56 269 56C212 56 118 102 118 241C118 346 175 401 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Journal of Oncology

fig5

Figure 5

Figure 5: SNHG3 Affects Gastric Cancer Development by Regulating SEPT9 Methylation 