IL-2 Modulates TAMs Derived Exosomal MiRNAs to Ameliorate Hepatocellular Carcinoma Development and Progression

Figure 2

The effects of the exosomes on HCC cell proliferation and apoptosis. (a) Representative immunostaining images of EdU⁺ cells in vitro. (b) Percentages of EdU⁺ nuclei over total number of nuclei. (c–e) Western blot analysis of PCNA and cyclin D1 expression. (f–g) Flow cytometry for Annexin V-APC and propidium iodide (PI) staining in cells treated with exosomes for 24 h. The representative plots (f) and quantification (g) are shown. (h–j) Western blot analysis of Bax and Bcl-2 expression. Error bars, SD. ; ; and .

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