IL-2 Modulates TAMs Derived Exosomal MiRNAs to Ameliorate Hepatocellular Carcinoma Development and Progression

Figure 4

The effects of the exosomes on HCC progression in vivo. ((a)–(c)) The morphological characteristics of tumor xenograft, tumor size, and tumor weight (n = 6 per group). (d) Representative photographs of Tunel-stained cancer sections from different groups. Apoptotic nuclei were identified by Tunel staining (red) and total nuclei by DAPI (blue). Scale bar: 50 mm. (e) Percentages of Tunel-positive nuclei over total number of nuclei. (f–h) Western blot analysis of Bax and Bcl-2 expression. (i–k) Western blot analysis of PCNA and cyclin D1 expression. Error bars, SD. ; ; and .

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