Research Article

Cost-Effectiveness Analysis of Follow-Up Schedule for Hepatocellular Carcinoma after Radiofrequency Ablation

Table 1

Base parameter input to model and ranges of sensitivity analysis.

ParametersBaseline valueRangeDistributionSource

Transition probabilities (monthly)
PFS to PD in the 2- to 3-month group1.18%0.59–2.36%Beta
PFS to PD in the 3- to 4-month group2.51%1.26–5.02%Beta

Costs per circle ($)
Two-month group monthly cost117.1658.58–234.32Gamma
Three-month group monthly cost78.1039.05–156.20Gamma

Utility value
Utility PFS0.760.61–0.91Beta[15]
Utility PD0.680.54–0.82Beta[15]
Discount rate5%0%–5%Fixed[16]

PD, progressive disease; PFS, progression-free survival.