Pancreatic Cancer-Derived Exosomes Promote the Proliferation, Invasion, and Metastasis of Pancreatic Cancer by the miR-3960/TFAP2A Axis

Figure 5

The effect of tumor-derived exosomes on the migration, invasion and apoptosis in miR-3960-overexpressed PANC-1 cells. (, n =3) (a) The migration of PANC-1 cells tested by Transwell assay. (×200) (b) The invasion of PANC-1 cells tested by Transwell assay. (c) The apoptosis of PANC-1 cells tested by flow cytometry. (d-f) The Bax and Bcl-2 protein levels measured by Western blot. P <0.05, P <0.01 compared to the miR-NC group, ^#P <0.05, ^##P <0.01 compared to the Exo + miR-NC group.

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