SHC1 Promotes Lung Cancer Metastasis by Interacting with EGFR

Figure 5

Overexpression of EGFR increases the cancer-promoting effect of SHC1. (a) Detection of SHC1 expression in NCI–H446 and A549 cells. (b) Detection of EGFR expression in NCI–H446 and A549 cells. (c) Detection of the cell proliferation rate of NCI–H446 and A549 cells. (d) Transwell detection of NCI–H446 and A549 cells. (e) Detection of the E-cadherin expression in NCI–H446 and A549 cells. (f) Detection of the vimentin expression in NCI–H446 and A549 cells. Data are shown as the mean ± SEM; n = 3 independent experiments, .

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