ANGPTL4 Regulates Lung Adenocarcinoma Pyroptosis and Apoptosis via NLRP3\ASC\Caspase 8 Signaling Pathway to Promote Resistance to Gefitinib

Figure 5

Effect of interfering ANGPTL4 on transplanted tumor tissue (, n = 3). (a) TUNEL assay was performed to detect the level of apoptosis in xenograft tissue (×400). (b) Ki-67 expression in the tumour tissue of each group. (c) ROS fluorescence staining was performed to detect the level of ROS in xenograft tissue (×400). (d) Flow cytometry showed the level of apoptosis in xenograft tissue. and : p < 0.05 and 0.001, respectively, compared to the control + G group; ^&and ^&&&: p < 0.05 and 0.001, respectively, compared to the ANGPTL4-shRNA3 group.

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