Long-Term Evaluation and Normal Tissue Complication Probability (NTCP) Models for Predicting Radiation-Induced Optic Neuropathy after Intensity-Modulated Radiation Therapy (IMRT) for Nasopharyngeal Carcinoma: A Large Retrospective Study in China

Table 2

Important dosimetric features and variables selected by the machine learning and LASSO.

	RFE	CoxBoost	RF-SRC	LASSO
1	Dmax	Dmax	Dmax	D50
2	D50	D50	D35	Dmin
3	/	D35	D1	/

Abbreviations: RFE = recursive feature elimination; CoxBoost = boosting in Cox regression; RF-SRC = random forests for survival, regression, and classification; LASSO = least absolute shrinkage and selection operator; Dmin = minimum point dose; Dmax = maximum point dose; D1-50 = minimum dose 1%-50% volume of the optic nerve or optic chiasma.