CircLATS2 Regulates miR-520a-3p/E2F7/p-VEGFR2 Signaling Pathway to Promote Hepatocellular Carcinoma Progression and Angiogenesis

Figure 2

CircLATS2 is a ceRNA of miR-520a-3p in HCC. (a) Binding sites of circLATS2 and miR-520a-3p. (b) Expression level of circLATS2 in PLC-PRF-5 and HepG2 cells. (c) Effect of circLATS2 on expression level of miR-520a-3p. (d) miR-520a-3p expression levels in paracancer and HCC tissues. The binding of CircLATS2 to miR-520a-3p was determined by dual luciferase reporter gene assay (e) and RNA pull-down (f). (g) Correlation between circLATS2 and miR-520a-3p. HCC: hepatocellular carcinoma.

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