hsa_circ_0077837 Alleviated the Malignancy of Non-Small Cell Lung Cancer by Regulating the miR-1178-3p/APITD1 Axis

Figure 4

APITD1 was a downstream molecule of miR-1178-3p. (a) TargetScan predicted the potential binding site between miR-1178-3p and APITD1. (b) Dual-luciferase reporter assays detected the regulation of miR-1178-3p on APITD1, and the data were presented as mean ± SEM, , miR-1178-3p mimics group vs. miR-1178-3p NC group. (c) miR-1178-3p expression was upregulated in 110 NSCLC tissues in comparison with 110 adjacent tissues, and U6 acted as a control, , tumor group vs. adjacent group. (d) APITD1 level affected by miR-1178-3p was detected by western blot, and the data were presented as mean ± SEM, , miR-1178-3p mimics group vs. NC group; , miR-1178-3p inhibitor group vs. NC group.

(a)

(b)

(c)

(d)