hsa_circ_0077837 Alleviated the Malignancy of Non-Small Cell Lung Cancer by Regulating the miR-1178-3p/APITD1 Axis

Figure 5

Hsa_circ_0077837 inhibited NSCLC cell growth by modulating the miR-1178-3p/APITD1 pathway. (a–d) The viability, migration, invasion, and apoptosis of H1650 cells were detected via CCK-8, transwell, would healing, and flow cytometry affected by miR-1178-3p or APITD1, respectively. , mimics group vs. NC group; , si-APITD1 group vs. NC group. (e–h) Rescue assays detected the rescue function of miR-1178-3p mimics or si-APITD1 to hsa_circ_0077837 elevation on viability, migratory, invasive, and apoptotic capabilities. , over-circ group vs. control group; , over-circ + mimics group vs. over-circ group; ^&, ^&&&, over-circ group + si-APITD1 group vs. over-circ group.

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