Identification of Prognostic Biomarkers of Glioblastoma Based on Multidatabase Integration and Its Correlation with Immune-Infiltration Cells

Table 4

Correlation analysis between TIMP1 and related genes and markers of immune cells in TIMER.

Description	Gene markers	GBM
		None		Purity
		Cor	P	Cor	P
CD8+ T cell	CD8A	0.093	0.251	−0.009	0.915
	CD8B	0.168	0.038	0.069	0.420
T cell (general)	CD3D	0.275		0.088	0.308
	CD3E	0.266		0.121	0.160
	CD2	0.273		0.092	0.285
B cell	CD19	0.043	0.600	−0.026	0.760
	CD79 A	−0.037	0.654	−0.087	0.313
Monocyte	CD86	0.313		0.111	0.198
	CSF1R	0.359		0.166	0.053
TAM	CCL2	0.579		0.490
	CD68	0.406		0.210	0.014
	IL10	0.397		0.214	0.012
Macrophage M1	NOS2	0.185	0.022	0.266
	IRF5	0.232		−0.005	0.954
	PTGS2	0.421		0.330
Macrophage M2	CD163	0.639		0.556
	VSIG4	0.470		0.316
	MS4A4A	0.498		0.380
Neutrophils	CEACAM8	−0.049	0.549	−0.086	0.315
	ITGAM	0.447		0.279
	CCR7	0.275		0.149	0.081
Natural killer cell	KIR2DL1	−0.007	0.929	−0.037	0.668
	KIR2DL3	−0.020	0.803	−0.083	0.335
	KIR2DL4	0.140	0.083	0.072	0.401
	KIR3DL1	0.036	0.656	0.023	0.793
	KIR3DL2	0.115	0.158	0.115	0.180
	KIR3DL3	0.034	0.675	−0.007	0.935
	KIR2DS4	0.174	0.032	0.136	0.112
Dendritic cell	HLA-DPB1	0.316		0.175	0.041
	HLA-DQB1	0.241		0.102	0.234
	HLA-DRA	0.339		0.167	0.051
	HLA-DPA1	0.223		0.100	0.245
Treg	STAT5B	−0.226		−0.132	0.124
	TGFB1	0.411		0.268

 < 0.01;  < 0.001;  < 0.0001.