Curcumol Targeting PAX8 Inhibits Ovarian Cancer Cell Migration and Invasion and Increases Chemotherapy Sensitivity of Niraparib

Figure 4

Curcumol inhibits the expression of PAX8 and inhibits the malignant progression of ovarian cancer cells. (a). Detection of PAX8 expression in IGROV-1 and OVCAR-3 cells after treatment with different concentrations of Curcumol (10, 20, 40 μM). (b). After treatment with different concentrations of Curcumol, the proliferation ability of IGROV-1 and OVCAR-3 cells was detected by CCK-8. (c). After treatment with different concentrations of Curcumol, the invasion ability of IGROV-1 and OVCAR-3 cells was detected by Transwell assay. P <0.05, P <0.01, P <0.001, vs Control group.

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