Acidic Tumor Microenvironment Promotes Pancreatic Cancer through miR-451a/MEF2D Axis

Figure 3

Tumor acidic microenvironment downregulated the expression of mitochondrial oxidative respiration-related gene miR-451a. (a) The functional enrichment analysis by g:Profiler software. (b) The expression of miR-199a-3p, miR-451a, miR-223-3p, miR-146-5p, and miR-21-5p detected by qRT-PCR. Error bars, mean ± SD from three independent experiments.  < 0.01;  < 0.001.

(a)

(b)