Upregulation of Metallothionein 1 G (MT1G) Negatively Regulates Ferroptosis in Clear Cell Renal Cell Carcinoma by Reducing Glutathione Consumption

Figure 5

Protein interaction network and GSEA of MT1G. (a) An interaction network of the MT1G protein with other proteins (MT1H, MT1X, MT1E, MT2A, MT1F, MT1M, APRT, SPINK7, GSR, and PLA2G2A). The interaction network was obtained from the STRING database. (b) The MT1G upregulated samples were enriched in pathway of “Oxidative phosphorylation.” (c) The MT1G upregulated samples were enriched in pathway of “P53 signaling pathway.” (d) The MT1G upregulated samples were enriched in pathway of “Proteasome.” (e) The MT1G upregulated samples were enriched in pathway of “Glutathione metabolism.”

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