Upregulation of Metallothionein 1 G (MT1G) Negatively Regulates Ferroptosis in Clear Cell Renal Cell Carcinoma by Reducing Glutathione Consumption

Table 1

Univariate analysis of the prognostic factors in ccRCC patients using a cox regression model.

Parameters OS	Univariate analysis		Multivariate analysis
	HR (95% CI)		HR (95% CI)
MT1G expression high vs. low	2.251 (1.497∼3.003)	<0.001	1.889 (1.596∼2.173)	<0.001
Age ≥ 65 vs. <65	1.022 (1.005∼1.041)	0.012	1.032 (1.012∼1.053)	0.002
Female vs. male	1.013 (0.666∼1.541)	0.951	1.222 (0.781∼1.913)	0.380
TMN stage III/IV vs. I/II	1.862 (1.541∼2.251)	<0.001	1.394 (0.829∼2.342)	0.210
Grade G1/2 vs. G3/4	2.242 (1.682∼2.988)	<0.001	1.486 (1.066∼2.071)	0.019
Invasion depth T1/2 vs. T3/4	1.943 (1.538∼2.456)	<0.001	1.033 (0.633∼1.685)	0.898
Lymph node metastasis	2.932 (1.516∼5.668)	0.001	1.582 (0.759∼3.296)	0.221
Distant metastasis	4.073 (2.634∼6.300)	<0.001	1.786 (0.793∼4.020)	0.161