Circular RNA hsa_circ_0004543 Aggravates Cervical Cancer Development by Sponging MicroRNA hsa-miR-217 to Upregulate Hypoxia-Inducible Factor

Figure 2

hsa_circ_0004543 silencing inhibited viability, colony formation, migration and invasion, and prompted apoptosis in CC cells. (a) The qRT-PCR assay validated successful hsa_circ_0004543 silencing with si-hsa_circ_0004543 in SiHa and C-4I cells. (b) Viability, (c) colony formation ability, (d) apoptosis, (e) migration capacity, and (f) invasion capacity of SiHa and C-4I cells after they were transfected with si-NC or si-hsa_circ_0004543 ( < 0.05 and  < 0.01).

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