lncRNA NEAT1 Promotes Colorectal Cancer Progression by Increasing Inflammation

<div>Knockdown NEAT1 attenuates tumor growth and inflammation-related gene expression <i>in-vivo.</i> (a) The tumorigenesis of nude mice. (b) The picture of tumor tissues of two groups. (c) Measurements of tumor tissue size. (d) Relative expression of genes in tumor tissues by qRT-PCR. (e) H&amp;E staining of tumor tissues. Scale bar indicates 200 <i>μ</i>m. (f) The expression of Ki-67 in tumor tissues was analyzed by immunohistochemistry. 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Unpaired two-tailed Student’s <svg height="8.02022pt" id="M36" style="vertical-align:-0.2063999pt" version="1.1" viewbox="-0.0498162 -7.81382 4.54925 8.02022" width="4.54925pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M324 430H196L233 583L223 592L145 529L120 430H54L29 396L31 388H111L56 126C33 15 54 -12 77 -12C137 -12 214 57 250 95L233 119C208 92 155 59 138 59C126 59 120 70 131 125L186 390L298 394L324 430Z"></path></g></svg> test between two groups was applied.</div>

Journal of Oncology

fig6

Figure 6

Figure 6: lncRNA NEAT1 Promotes Colorectal Cancer Progression by Increasing Inflammation 