ATAXIC: An Algorithm to Quantify Transcriptomic Perturbation Heterogeneity in Single Cancer Cells

Figure 5

Correlations of ATAXIC scores with DNA damage repair signatures in cancer. Spearman correlations between ATAXIC scores and the enrichment scores of the DNA damage signature (a), the mismatch repair pathway (b), and the homologous recombination pathway (c) in single cells from individual patients of eight cancer types. The Spearman correlation coefficients and adjusted P values (FDR) are shown.

(a)

(b)

(c)